Supplementary Figure 9: miR-137-mediated regulation of the genes implicated in neuropsychiatric disorders. | Nature Neuroscience

Supplementary Figure 9: miR-137-mediated regulation of the genes implicated in neuropsychiatric disorders.

From: Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a

Supplementary Figure 9

Venn diagrams show overlaps among the disease candidate genes with the differentially expressed (DE) proteins (that is, 377 DE genes) that identified by proteomics analysis (Mir137–/–versus Mir137+/+). The upregulated DE (DEup) and downregulated DE (DEdown) genes overlapped with ASD-, schizophrenia (SCZ)-, Intellectual disability (ID)-candidate genes, then overlapped with miR-137 predicted targets. Pearson’s chi-squared test calculated the P-value.

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