Supplementary Figure 9: Arborization and synapse analysis of Pcdha KO mice. | Nature Neuroscience

Supplementary Figure 9: Arborization and synapse analysis of Pcdha KO mice.

From: Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell–derived cortical interneurons from subjects with schizophrenia

Supplementary Figure 9

Related to Fig. 5. (a) Tracing of PV+ cINs in the PFC of littermate wild type or Pcdha KO (Pcdha Δα/Δα) mice (n = 100 neurons). Neurites within 150 µm of the center of PV+ cell body were traced (Scale bar = 50 µm). (b) GABAergic synapse analysis of Pcdha KO versus wild type litter mates (n = 25 images, scale bar = 5 µm). (c) Glutamatergic synapse analysis of Pcdha KO versus wild type litter mates (n = 25 images, scale bar = 5 µm).

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