Extended Data Fig. 3: Co-culture with activated microglia results in dysregulated metabolic gene pathways in developmental cINs. | Nature Neuroscience

Extended Data Fig. 3: Co-culture with activated microglia results in dysregulated metabolic gene pathways in developmental cINs.

From: Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia

Extended Data Fig. 3

a, Expression of CTGF in HC cINs and SCZ cINs with or without co-culture with activated microglia, analyzed by qPCR analysis. Paired data from the same line are connected by a solid line. b, Expression of THBS1 in HC cINs and SCZ cINs with or without co-culture with activated microglia, analyzed by qPCR analysis. Paired data from the same line are connected by a solid line. c, Expression of KLF5 in HC cINs and SCZ cINs with or without co-culture with activated microglia in the pilot cohort, analyzed by qPCR analysis. Paired data from the same line are connected by a solid line. d, Expression of KLF5 in HC cINs and SCZ cINs with or without co-culture with activated microglia in the replication cohort, analyzed by qPCR analysis. Paired data from the same line are connected by a solid line.

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