Extended Data Fig. 9: Layer and region-dependent proportions of MOL1, MOL2/3, and MOL5/6 across healthy aging and cuprizone treatment. | Nature Neuroscience

Extended Data Fig. 9: Layer and region-dependent proportions of MOL1, MOL2/3, and MOL5/6 across healthy aging and cuprizone treatment.

From: Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis

Extended Data Fig. 9

Related to Figs. 7,8. a) Raw counts of the total # of segmented Mobp-EGFP OLs (top), MOL1+ OLs (row 2), MOL2/3+ OLs (row 3) and MOL5/6+ OLs (bottom) across cortical and subcortical layers (x-axes) and experimental time points (shaded background colors). Data are from n = 6 mice (Healthy P60), n = 8 mice (Healthy P140), n = 5 mice (Cup. + 4 days) and n = 7 mice (Cup. + 7 weeks), 2 sections per mouse. Bar graphs represent the mean + /- SEM. Data presented in the main figures were expressed either as the percentage of total OLs for each probe (Figs. 7–8), or the change in proportion of each marker from the healthy P140 time point (Figs. 4–6).

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