Extended Data Fig. 8: Overexpression of futsch in glia disrupts LD formation similar to hTau overexpression. | Nature Neuroscience

Extended Data Fig. 8: Overexpression of futsch in glia disrupts LD formation similar to hTau overexpression.

From: Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress

Extended Data Fig. 8

Rh:ND42 RNAi was used to induce neuronal ROS and glial LD. LDs were visualized in fly retinas of 2d animals using BODIPY 493/503 (white puncta, arrows). UAS-Control (LacZ), UAS-futsch, or UAS-ensconsin (ens) were overexpressed in glia using 54C-GAL4. A datapoint represents the average LD number per ommatidium per animal (n). n = 7-8. Statistics: 1-way ANOVA with Tukey’s multiple comparisons test. P-values = not significant (n.s.) >0.05, *≤0.05, **≤0.01, ***≤0.001, ****≤0.0001. Data presented as mean ± SEM. See Supporting Data 1 for details on n and P-values.

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