Extended Data Fig. 7: Expression of pattern recognition receptors in the brain and peripheral tissues in COVID-19 cases. | Nature Neuroscience

Extended Data Fig. 7: Expression of pattern recognition receptors in the brain and peripheral tissues in COVID-19 cases.

From: Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19

Extended Data Fig. 7

mRNA levels of different PRRs were measured by qPCR in tissue homogenates. Kruskal-Wallis test with Dunn's multiple comparisons (all groups compared): *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001; brain areas compared: #p<0.05, ##p<0.01, ###p<0.001 vs medulla; $p<0.05, $$p<0.01 vs hypothalamus. Data from n=11 COVID-19 cases. Refer to Supplementary Table 2 for details on significant differences between groups and related P values. Data are presented as mean ± SEM.

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