Extended Data Fig. 6: Astrocyte-specific CLEC16A deletion in CLEC16AGFAP mice.
From: CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model
(a,b) IHC analysis of CLEC16A (Green), GFAP (purple) in spinal cord sections from Control EAE or CLEC16AGFAP EAE mice (day 21); representative maximum intensity images of Z-stacks are shown. Scale bars 200 μm (upper images) and 30 μm (lower images). (c) Quantification of CLEC16A expression in astrocytes (GFAP), neurons (Neurofilament-L), and microglia (IBA1) are shown. Each condition is quantified from 6 images, containing 2 independent images of whole spinal cord sections from 3 mice. **** p < 0.0001, n.s. not significant by Sidak’s test.
