Extended Data Fig. 2: Functional profiling of sequences involved in dimerization.
From: Short- and long-range interactions in the HIV-1 5′ UTR regulate genome dimerization and packaging
Functional profiling of sequences involved in dimerization by analysed by mutational interference. kdimer is a relative measure of the effects of a mutation on dimerization. median log2(kdimer) values for each genome position for all three uncapped transcript variants in high and low salt buffers. Thin lines are unsmoothed data, whereas thick lines are smoothed with a window size of 5 nt. log2(kdimer) values for (a) high salt uncapped transcripts (b) low salt uncapped transcripts (c) high salt capped transcripts (d) low salt capped transcripts.
