Extended Data Fig. 8: N-linked glycan conservation across diverse primate immunodeficiency viruses. | Nature Structural & Molecular Biology

Extended Data Fig. 8: N-linked glycan conservation across diverse primate immunodeficiency viruses.

From: Cryo-EM structures of prefusion SIV envelope trimer

Extended Data Fig. 8

(top) Bar graph depicting the percent conservation of N-linked glycan sequon positions (HXB2 numbering from 1–683) for the 34 viruses depicted in the phylogenetic tree of Fig. 4. Hypervariable regions extending beyond HXB2 numbering are excluded due to high variability and low confidence alignments. * at positions 143 and 185 denotes artificially high bars due to multiple glycans in inserts. Dotted horizontal lines are shown at 50% and 75% conservation and locations above these thresholds are labeled. (bottom) A detailed plot of sequon locations for all 34 sequences in the phylogenetic tree of Fig. 4. Locations are colored as in Fig. 4b.

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