Fig. 3: Movement of the +1 nucleosome upon NTP addition. | Nature Structural & Molecular Biology

Fig. 3: Movement of the +1 nucleosome upon NTP addition.

From: Structures of transcription preinitiation complex engaged with the +1 nucleosome

Fig. 3

a, Rotation of the +1 nucleosome as observed by comparison of complex A (light colors, without NTPs) and complex B (full colors, with NTPs). b, Detachment of promoter-proximal, terminal nucleosomal DNA from the histone octamer. Terminal nucleosomal DNA is displaced by roughly 20° and 60° in complexes A and B, respectively, with respect to the canonical nucleosomal DNA path (orange). The nucleosome dyad is indicated in black.

Back to article page