Extended Data Fig. 8: Conformational change between P116 and P116 empty. | Nature Structural & Molecular Biology

Extended Data Fig. 8: Conformational change between P116 and P116 empty.

From: Essential protein P116 extracts cholesterol and other indispensable lipids for Mycoplasmas

Extended Data Fig. 8

Superimposition of one subunit of P116 with one subunit of P116 empty. The movement of the fingers 1-4 is indicated by dashed lines. Side view of the ribbon representation of the empty and full P116 shows that the fingers (in purple) have come closer to the core ___domain, massively reducing the available volume. Their new position is markedly different compared to the full P116 (shown in light blue). Finger 1 moved 8 Å sideways and towards the core, finger 2 has moved 13 Å towards the core and Finger 3 has moved 12 Å towards the core.

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