Extended Data Fig. 3: Dimerization interface and model building of P116.
From: Essential protein P116 extracts cholesterol and other indispensable lipids for Mycoplasmas
Detail of the dimerization zone with the two monomers and the TRP-681 residue of both chains contacting the opposite one. (b) SEC-MALS of P116 W681A. The greatest polydispersity of this sample is observed, which oscillates between a very large MW (molecular weight) range, and the clear decrease in size with respect to the WT due to the now predominance of the monomeric state. (c) Exemplary superimpositions of the cryoEM density and the PDB model for the core and N-terminal ___domain.
