Extended Data Fig. 5: SAXS analysis of the experimental profiles and the calculated profiles.

a-c. The experimental SAXS scattering curve of wild-type FluPol H5N1 (gray) fits with the calculated curves of the intermediate FluPolH5N1 (a, black), transcriptase (b, blue, 5MSG) and replicase (c, green, 6XZG), respectively. d, e. The experimental profiles of E517A (d, red) and K586A/R589A (e, orange) fit the calculated profiles from transcriptase (blue, 5MSG). f, g. The experimental profiles of E517A (f, red) and K586A/R589A (g, orange) fit the calculated profiles from replicase (green, 6XZG). The χ2 value is shown as indicated. Data were analyzed by BioXTAS RAW and ATSAS packages.