Extended Data Fig. 8: Structure of the Rpd3S-di-nucleosome complex. | Nature Structural & Molecular Biology

Extended Data Fig. 8: Structure of the Rpd3S-di-nucleosome complex.

From: Structure of histone deacetylase complex Rpd3S bound to nucleosome

Extended Data Fig. 8

a, Model fitted into the Rpd3–di-nucleosome complex reconstruction. Low-threshold contoured map of the complex is displayed as semitransparent surface. A model of Rpd3S bound to di-nucleosome was nicely fitted into the density. b, The second copy of the Eaf3-Rco1 module might bind the N-terminal tail of histone H3 from a neighbouring nucleosome. Focused refinement map of Eaf3-Rco1in Rpd3S–mono-nucleosome reconstruction shown at low threshold revealed a weak density could be assign to the histone H3 N-terminus from the neighbouring nucleosome at the binding surface of the second Rco1 PHD1.

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