Extended Data Fig. 4: Cryo-EM analysis of the Pol II-CSA-DDB1-CSB-ELOF1 complex.

a. Processing tree. The number of particles included in refined maps is indicated below the map, together with the map resolution. Classes used for further processing are color-coded according to complex subunits. Classification revealed particles with CSA docked onto ELOF1 and particles with CSA not docked onto ELOF1. Particles with docked CSA were further processed to demonstrate data quality. b. Local resolution estimate for the composite map. c. Fourier shell correlation plot for all focused refined maps and the composite map. d. Angular distribution plot for the high-resolution Pol II class used as a starting point for focused classifications.