Extended Data Fig. 6: Further analysis of TFE3 binding levels at TET-target and control regions.
From: TET activity safeguards pluripotency throughout embryonic dormancy
a. Heatmaps showing TET occupancy (TET1), DNA methylation (WGBS), and genome accessibility (ATAC-Seq) at TET-dormancy-targets vs control regions. b. RNA expression levels (TPM) of the transcription factors shown in Fig. 5a and b. c. Boxplots showing TFE3 binding levels at TET-dormancy-targets and control regions. Horizontal lines denote the median, lower and upper hinges denote the first and third quartiles. Whiskers show 1.5 times the interquartile range. d. Western blot showing Flag-immunoprecipitated material from Tet1-Flag and wild-type ESCs. Three biological replicates were performed.
