Fig. 3: XIST is broadly distributed on the dampened X chromosome in naive hES cells.
From: XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
a, Analysis by RT–qPCR of XIST and JPX enrichment after XIST pulldown in naive and primed H9 hES cells. JPX was used as a negative control. Values were normalized to the input (n = 2). b, Percentage of aligned DNA sequencing reads per chromosome after XIST pulldown and in input material in naive and primed H9 hES cells (n = 2). c, Percentage of XIST RAP peak occupancy per chromosome for primed and naive H9 hES cells (n = 2). d, XIST RAP profiles (log2 enrichment over input) on the X chromosome in naive and primed H9 hES cells. e, Profile plots of XIST RAPseq reads over a 10-kb region flanking the TSSs of X-linked genes in naive and primed H9 hES cells.
