Extended Data Fig. 4: Synergistic binding of the MDs of Hsp90 to clients.
From: Structural basis for the dynamic chaperoning of disordered clients by Hsp90
a-d, Overlay of 1H–15N HSQC spectra of Δ131Δ fragments and FtsZC in the absence and presence of Hsp90NM (a), Hsp90MC (b), Hsp90MCLC (c) and the dimerized Hsp90MM (d). These data collectively demonstrate a significant binding synergy between Hsp90M and clients.
