Extended Data Fig. 3: 3′ ssDNA encounters a negatively charged patch on the C-terminal helix of D5 at the PolθH DNA tunnel exit.
From: Human polymerase θ helicase positions DNA microhomologies for double-strand break repair
DNA from the PolθH-DNA searching model is merged with the apo PolθH dimer model. The D5 surface of one PolθH protomer is colored by electrostatic potential, and the ratchet helix is colored pink.
