Figure 1

Representative overlapped 2D-DIGE gel image of SVZ+ and SVZ- GBM patient’s serum proteome and 3D-views of significantly altered proteins. Extracted serum proteome from SVZ+ (n = 8) and SVZ- (n = 8) GBM patients were labeled with respective CyDyes and separated on IPG strips of pH 4–7; 18 cm followed by separation on 12.5% SDS polyacrylamide gels. 2D-DIGE analysis was performed using DeCyder 2D software version 7.0 and the identities of significantly altered protein spots were established using MALDI-TOF/TOF analysis (Green colour indicates Cy3 labeled protein and red colour indicates Cy5 labeled protein).