Figure 3

TCAB1 is involved in the promotion of telomerase activity induced by EBV. A telomerase assay was performed using telomerase PCR-ELISA. A lysate of 293 cells was heated at 85 °C for 10 min as the negative control; the unheated lysate was used as the positive control. The error bars represent the mean ± SD values. The statistical analysis was performed using Student’s t test (^aP < 0.05, ^bP < 0.01, comparing with EBV-negative CNE1; ^cP < 0.05, ^dP < 0.01, comparing with EBV-negative CNE1-LMP1). Telomerase was activated by EBV in CNE1 and CNE1-LMP1 cells, and inhibited by TCAB1 depletion in EBV-positive cells.