Figure 4

Content of IL-6 (A), IL-1β (B), leptin (C), VCAM-1 (D) and ICAM-1 (E) by epididymal adipose tissue and of IL-6 (F), TNF-α (G) and nitric oxide (H) by LPS-stimulated peritoneal macrophages (1 × 106 cells) from C57BL/6 mice fed the control diet (CD) or obesogenic diets (high-sugar (HS), high-fat (HF) or high-sugar/high-fat diet (HSHF) for eight weeks. The results are expressed as the mean ± S.E.M. (n = 4–7/group). (a) P < 0.05 compared with CD, (b) P < 0.05 compared with HS, and (c) P < 0.05 compared with HF, using the one-way ANOVA and Tukey’s post-test. VCAM, vascular cell adhesion protein 1; ICAM, intercellular cell adhesion molecular 1; IL, interleukin; LPS, lipopolysaccharide from E. coli 055:B5 (2.5 μg/mL for 24 h).