Figure 4

MR images of the excised tissues containing the sentinel lymph node (green shortshafted arrow) and control node (yellow long-shafted arrow) for animal 2 (detectable with MMUS) and animal 4 (not detectable with MMUS). Both lymph node samples (together with some of their surrounding tissue) were placed in an Eppendorf tube during the MRI acquisition. The superparamagnetic nanoparticles present in the sentinel lymph node are shown as hypoenhanced voids (black). The black areas around and in between the two tissue samples stem from air pockets. A considerably larger hypoenhancement can be seen for animal 2 compared to animal 4.