Figure 5 | Scientific Reports

Figure 5

From: Systematic discovery of genetic modulation by Jumonji histone demethylases in Drosophila

Figure 5

NO66 KO strongly modifies a growth phenotype in the eye. (A,CE) Adult eyes of the indicated genotypes. (A) ey-Gal4 UASt-Taf1B-RNAi/ + displays an eye to antenna transformation in ~35% of progeny. (B) A graph representing the number of eye to antenna transfomations in the genotypes ey > Taf1B-RNAi/ + with JmjC KO/+, or UASp-NO66. *P < 0.005. (C) NO66 KO/+ suppresses the phenotype, and (D) UASp-NO66 enhances the phenotype, while (E) overexpression of NO66 alone has no phenotype. (F,G”) Salivary gland cells of the genomic tag NO66::HA stained with anti-HA (green, NO66), anti-Fib (red) and DAPI (blue), followed by single channels in greyscale. (H,I”) Salivary gland cells of the genomic tag NO66::HA stained with anti-HA (green, NO66), anti-Udd (red) and DAPI (blue), followed by single channels in greyscale. Scale bar is 20 μm.

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