Table 2 Univariate and multivariate cox regression analysis for development of primary open angle glaucoma after retinal vein occlusion during an eleven-year follow-up period.

From: Health care claims for primary open-angle glaucoma and retinal vein occlusion from an 11-year nationwide dataset

Variable

Univariate Cox

Multivariate Cox

HR

95% CI

P Value

HR

95% CI

P Value

Group

Comparison group

1 (ref)

  

1 (ref)

  

RVO group

3.25

2.39–4.42

<0.001

2.16*

1.58–2.94

<0.001

Hypertension

No

1 (ref)

  

1 (ref)

  

Yes

2.48

2.33–2.64

<0.001

1.91

1.78–2.05

<0.001

Diabetes mellitus

No

1 (ref)

  

1 (ref)

  

Yes

1.88

1.73–2.04

<0.001

1.42

1.30–1.56

<0.001

Dyslipidemia

No

1 (ref)

  

1 (ref)

  

Yes

2.16

1.98–2.35

<0.001

1.19

1.08–1.30

<0.001

Age group (yrs)

40–64

1 (ref)

  

1 (ref)

  

≥65

2.14

2.01–2.28

<0.001

1.64

1.54–1.76

<0.001

Gender

Male

1 (ref)

  

1 (ref)

  

Female

1.25

1.17–1.32

<0.001

1.16

1.09–1.23

<0.001

Household income

0–50%

1 (ref)

  

1 (ref)

  

50–100%

1.06

1.10–1.13

0.048

1.09

1.02–1.16

0.009

Residential area

Seoul (metropolitan)

1 (ref)

  

1 (ref)

  

Other

1.01

0.95–1.07

0.796

0.96

0.90–1.02

0.206

  1. RVO = retinal vein occlusion, HR = hazard ratio, CI = confidence intervals. *Adjusted for age, gender, income, residential area, hypertension, diabetes mellitus, dyslipidemia.
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