Figure 2 | Scientific Reports

Figure 2

From: Effects of low-intensity pulsed electromagnetic fields on bone microarchitecture, mechanical strength and bone turnover in type 2 diabetic db/db mice

Figure 2

Effect of PEMF stimulation on body weight, blood glucose and serum bone turnover markers in db/db mice. The db/db mice showed significantly higher body weight (A) and blood glucose (B) than the WT group both before and after 12-week experiment, whereas 12-weeek PEMF exposure exhibited no apparent effect on body weight or blood glucose in db/db mice. The db/db mice also exhibited decrease in bone formation marker (C) osteocalcin (OCN) and increase in bone resorption marker (D) tartrate-resistant acid phosphatase 5b (TRACP5b). PEMF promoted serum OCN secretion, whereas PEMF displayed no observable effect on serum TRACP5b expression. WT, the wild-type mice group; db/db, the db/db mice group; PEMF, the db/db mice with PEMF stimulation group. Values are all expressed as mean ± S.D. (n = 9). *Significant difference from the WT group with P < 0.05; #Significant difference from the db/db group with P < 0.05.

Back to article page