Table 2 Clinical characteristics and genetic testing results of the HF patients.
Patients | Age/Gender | Family History of SCD | Arrhythmias | Risk Factors | Pacing Mode | Baseline Echocardiography | Duration of HF Onset (months) | Follow-up Echocardiography | Genetic Testing Results | Mutation Prediction | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
LVEF (%) | LVEDD (mm) | LVEF (%) | LVEDD (mm) | |||||||||
1 | 39/M | Yes | III AVB, AF | HT | VVI | 70 | 57 | 28 | 39 | 59 | LMNA p. Leu379Val | Pathogenic |
2 | 41/M | Yes | III AVB, AF, PVC, VT | None | VVI | 63 | 56 | 13 | 31 | 65 | LMNA c.1157 + 1 G > T | Pathogenic |
3 | 57/M | None | III AVB | None | DDD | 64 | 47 | 12 | 45.5 | 58 | TTN p. Glu5365Asp; TTN p.Arg3067His | Pathogenic; VUS |
4 | 37/F | None | III AVB | None | DDD | 53 | 62 | 15 | 42.5 | 70 | DSP c.1140 + 6 T > C | VUS |
5 | 54/F | None | IIIAVB, PVC, VT, VF | None | DDD | 62 | 55 | 30 | 25 | 64 | CACNA1C c.372-9 C > G; CACNA1C c.4074 + 6 C > T | VUS; VUS |
6 | 64/F | Yes | III AVB, AF | HT | DDD | 52 | 52 | 25 | 35.6 | 54 | LMNA p. Arg216Cys | Pathogenic |
7 | 39/F | None | III AVB | None | DDD | 60 | 57 | 6 | 39 | 59 | DSG2 p. Leu563Arg; AKAP9 c.9358 + 10 A > G | VUS; VUS |
8 | 46/M | None | III AVB, CLBBB | None | DDD | 60 | 55 | 28 | 45 | 59 | TTR p. Ser43Asn; DSG2 p. Phe531Cys; CSRP3 p. Gly72Arg | Pathogenic; Pathogenic; Pathogenic |
9 | 60/F | None | III AVB | HT | DDD | 63 | 47 | 24 | 28 | 61 | MYH7 p. Glu1902Gln; TTN p. Arg8985Cys | Pathogenic Pathogenic |
10 | 39/M | Yes | III AVB | None | DDD | 54 | 54 | 8 | 42 | 58 | MYBPC3 p. Gly507Arg | Pathogenic |
