Figure 6 | Scientific Reports

Figure 6

From: ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury

Figure 6

Blast induces GSK3β activation in ApoE4 mice and synj1 knockdown reduces pTau through inactivation of GSK3β. Levels of (A) active and (B) inactive pGSK3β after blast. Results are presented as % of controls ± SEM (ApoE3 sham). Levels of (C) active pGSK3β and (D) pTau in N2a cells with synj1 siRNA, GSK inhibitors, or combination. Results are presented as % of controls ± SEM.

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