Figure 3 | Scientific Reports

Figure 3

From: Altered methylations of H19, Snrpn, Mest and Peg3 are reversible by developmental reprogramming in kidney tissue of ICSI-derived mice

Figure 3

Pyrosequencing analyses of the methylation profiles from ICSI-derived, TCET conceived and natural mating mice of adult and old age. There are 3 CpG sites for the H19 DMR (a), 5 CpG sites for the Snrpn DMR (b), 4 CpG sites for the Mest DMR (c) and 5 CpG sites for the Peg3 DMR (d) (t-test was used for the analysis. ICSI versus TCET: **p < 0.01; *p < 0.05. TCET versus Nature: ##p < 0.01; #p < 0.05). The pyrogram of pyrosequencing of one sample in each gene and each group was shown in Supplementary Figure S1.

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