Table 3 Average COH of tensors over all pairs of datasets used in T1_normalized, FA_normalized, and hFA_normalized.

Brain Region	FA_normalized		T1_normalized		hFA_normalized		F	P	P1	P2	P3
Brain Region	mean	STD	mean	STD	mean	STD	F	P	P1	P2	P3
ALIC	0.890	0.047	0.879	0.049	0.834	0.105	180.431	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
CG	0.749	0.126	0.660	0.156	0.659	0.147	179.477	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
EC	0.853	0.092	0.833	0.085	0.810	0.099	105.047	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
fornix	0.864	0.052	0.847	0.081	0.765	0.196	99.418	<10⁻¹⁰	0.087	<10⁻¹⁰	<10⁻¹⁰
GCC	0.848	0.097	0.782	0.137	0.722	0.162	216.864	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
PLIC	0.912	0.030	0.890	0.049	0.876	0.174	57.977	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
SCC	0.844	0.126	0.814	0.109	0.800	0.193	332.911	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
CST	0.823	0.107	0.798	0.101	0.732	0.103	166.223	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰	<10⁻¹⁰
SLF	0.701	0.150	0.671	0.140	0.595	0.167	155.456	<10⁻¹⁰	0.007	<10⁻¹⁰	<10⁻¹⁰
IFOF	0.839	0.116	0.833	0.081	0.799	0.155	6.764	0.031	0.603	0.0005	<10⁻¹⁰

ALIC: anterior limb of the internal capsule, CG: cingulum, EC: external capsule, fornix, GCC: genu of the corpus callosum, PLIC: posterior limb of the internal capsule, SCC: splenium of the corpus callosum, CST: corticospinal tract, SLF: superior longitudinal fascicle, IFOF: inferior fronto-occipital fasiculus. COH: coherence of primary eigenvectors. ANOVA was used to compare the difference between the three diffusion tensor templates. P1: Statistically significant differences between FA_normalized and T1_normalized (after correction for multiple comparisons with the Bonferroni approach). P2: Statistically significant differences between T1_normalized and hFA_normalized (after correction for multiple comparisons with the Bonferroni approach). P3: Statistically significant differences between FA_normalized and hFA_normalized (after correction for multiple comparisons with the Bonferroni approach).

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