Figure 2 | Scientific Reports

Figure 2

From: Genome-wide open chromatin regions and their effects on the regulation of silk protein genes in Bombyx mori

Figure 2

The distribution and function of OCRs. (a) Profile and heatmap of open chromatin regions (OCRs) of Bombyx mori embryo-derived (BmE) cells and silk glands. The distribution profile of OCRs within+/−2 kb of transcriptional start sites (TSS). Heatmap of TSS+/−2 kb region OCRs were clustered using k-means = 4. The number of OCRs in every cluster was marked in the picture both silk gland and BmE cell. (b) The genomic ___location of OCRs. Orange bar represents silk gland OCRs; blue bar represents BmE OCRs. (c) OCRs and regulated genes of BmE cells and silk glands. Up-regulated and down-regulated genes are considered those whose expression level was significantly higher or lower in the silk gland than in BmE cells, respectively. OCRs located within 2 kb of a gene were considered that adjacent gene’s OCR. Orange bar represents genes; blue bar represents OCRs.

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