Figure 6 | Scientific Reports

Figure 6

From: Calcineurin/P-ERK/Egr-1 Pathway is Involved in Fear Memory Impairment after Isoflurane Exposure in Mice

Figure 6

Injection of FK506 after isoflurane exposure attenuated isoflurane anesthesia-induced P-ERK decrease of mice. (A) In the hippocampus, FK506 reversed the reduced P-ERK/ERK by isoflurane in the vehicle groups detected after the short-term and long-term fear memory tests; (B) In the amygdala, FK506 reversed the reduced p-ERK/ERK by isoflurane in the vehicle groups detected after the short-term and long-term fear memory tests. ## P < 0.05, ### P < 0.001.

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