Figure 2

M2 macrophage (CD206+) cell count. The M2 macrophages were stained in brown, and the total area occupied by these cells was measured. Sham animals presented no M2 macrophages; I + PY group showed higher infiltration of CD206 + cell within the infarcted and peri-infarcted zone when compared to the I group (P = 0.04, Kruskal-Wallis test). The I group and I + PY were statistically different from the Sham group (P = 0.003 and P < 0.0001, respectively, Kruskal-Wallis). Values are expressed as mean ± SEM. (Immunohistochemistry, DAB, scale bar 400 μm).