Figure 6
From: A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice
Aberrant production of human pro-inflammatory cytokines. (a) Levels of human proinflammatory cytokines, as indicated, in the blood serum and peritoneal lavage fluid (lavage) of control and pristane-injected hu-mice were measured by a multiplex bead-based immunoassay at 8 weeks after pristane injection. Figure shown is from five independent experiments (control n = 19; pristane n = 17).Ct: control; Pr: pristane. (b) Gene expression level of type I IFN target genes in human hepatocytes in control and pristane-injected humice at four weeks after pristane injection. Data is representative of three independent experiments (control n = 10; pristane n = 10). *P < 0.05; ***P < 0.001; ****P < 0.0001
