Figure 6 | Scientific Reports

Figure 6

From: The Toll–Like Receptor 2/6 Agonist, FSL–1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome

Figure 6

FSL–1 enhances peripheral blood repopulation. Male C57BL/6 mice were administered physiological water (NT) or FSL–1 at 24 hours post 9.2 Gy TBI. Peripheral blood was collected with (a) white blood cell, (b) lymphocyte, (c) granulocyte, (d) monocyte, (e) red blood cell and (f) platelet populations counted. The number of mice examined are: n = 3 for NT and FSL–1 only groups; n = 6 for TBI, NT mice; n = 6–9 (days 3 and 9); n = 7 (day 17) and n = 10 (day 31) for TBI, FSL–1–treated mice. Data are represented by mean ± s.e.m., and are tallied from 2–3 independent experiments. Each symbol represents one mouse. *P < 0.05 or **P < 0.01 between TBI, NT and TBI, FSL–1–treated mice. + P < 0.05, ++ P < 0.01, +++ P < 0.001 or ++++ P < 0.0001 between TBI, FSL–1 and FSL–1 only treated mice. δ P < 0.05, δδ P < 0.01, δδδ P < 0.001 or δδδδ P < 0.0001 between TBI, NT and NT control mice.

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