Figure 1

Schematic flow chart and the illustrative result of rs-fMRI-based automatic tumor tissue identification. (a) Mean image of a rs-fMRI data; (b) raw 3D T1 image; (c) T1 image co-registered to the mean rs-fMRI image; (d) initial tumor template; (e) the curve of the largest DICI values plotted against different TNCs settings; (f) final tumor-related component with the largest DICI value across all TNCs settings; and (g) a tumor-related component candidate corresponding to the largest DICI value for TNCs = 90 (but not the optimal TNCs).