Figure 1 | Scientific Reports

Figure 1

From: Angiotensin-converting enzyme inhibitor reduces scar formation by inhibiting both canonical and noncanonical TGF-β1 pathways

Figure 1

ACEI reduced fibroblast proliferation and collagen expression. (A,B) Proliferation of NIH 3T3 cells treated without (A) or with (B) 1.0 ng/ml TGF-β1 were measured with CCK-8. (C) Total collagen was detected in NIH 3T3 cells (3T3, NIH 3T3 cells; Lis, 10 μM lisinopril; TGF-β1, 1.0 ng/mL TGF-β1). NIH 3T3 mouse cells were cultured for 72 h in DMEM with 1% FBS. *P < 0.05.

Back to article page