Figure 5 | Scientific Reports

Figure 5

From: Angiotensin-converting enzyme inhibitor reduces scar formation by inhibiting both canonical and noncanonical TGF-β1 pathways

Figure 5

ACEI inhibited SMAD2/3 and TAK1 pathways in vivo. (A) Expression levels of ACE, TGF-β1, SMAD2/3, TAK1, collagen I and collagen III mRNA in scar tissues. (B) Western Blotting analysis of TGF-β1, p-SMAD2/3, p-TAK1, collagen I and III, and ACE in scar tissues. Full-length gel is shown in Supplementary Fig. 4. *P < 0.05 compared with the blank control group.

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