Figure 3
From: Cerebral blood flow predicts differential neurotransmitter activity
Results of correlational analyses with molecular imaging based receptor density estimates and affinities. (a) Correlational plots between regional cerebral blood flow (CBF) changes and respective dopamine transporter (DAT) density profiles are displayed for each drug with dopaminergic mechanism of action. (b) DAT density estimates obtained from a healthy volunteer cohort provided by the Parkinson’s Progression Marker Initiative. (c) Correlational plot between midazolam induced CBF changes and GABAa density estimates obtained from flumazenil positron emission tomography. (d) Correlations of cerebral blood flow (CBF) changes to receptor density profiles with drug affinities. Colors indicate different receptors. Shapes indicate different drugs. Solid line in all plots indicates the linear regression fit.
