Figure 9
Hematological analysis of LL/2-bearing ICR mice treated with SaM. Low dose = 2 mg/mouse; High dose = 6 mg/mouse. (a) Red blood cell and (b) white blood cell counts of control, water-fed, and SaM treated mice. Data are expressed as average total cell number ± SEM. (c–f) Leukocyte analysis: T cell, B cell, granulocytes, and macrophage cell counts. Data are expressed as average percentage ± SEM. The average percentage was calculated by dividing the number of T cells, B cells, granulocytes, or macrophage cells by total number of leukocytes. (g) Hemoglobin content of peripheral blood. Data are expressed as absorbency at wavelength of 570 nm ± SEM. (h) Hematopoietic stem cell (LSK) analysis. Average percentage of hematopoietic stem cell (±SEM) was calculated by dividing the number of LSK cells by total viable bone marrow cells. Statistical differences between the control and the treated groups were determined with a one-way ANOVA followed by the Dunnett’s post-hoc test when results of the ANOVA were significant: *p < 0.05 vs. control.
