Table 1 Demographic information of the control group, NCI group and CI group.

From: The Relationship between Cerebral White Matter Integrity and Cognitive Function in Mild Stroke with Basal Ganglia Region Infarcts

 

Control group (n = 19 cases)

NCI group (n = 13 cases)

CI group (n = 20 cases)

p1 value

p2 value

p3 value

Age (years, mean ± SD)

50.74 ± 7.37

54.61 ± 9.11

48.15 ± 8.32

0.40

0.17

0.06

Sex (male/total, %)

13/19 (68.42)

11/13 (84.62)

16/20 (80.00)

0.40

0.48

 

Education (years, mean ± SD)

10.68 ± 2.38

9.40 ± 1.73

10.84 ± 1.99

0.84

0.06

0.04

NIHSS at admonition [scores, median (IQR)]

—

2.00 (2.50)

2.00 (2.75)

—

—

0.43

Functional status (Modified Rankin Scale; [scores, median (IQR)])

—

1.00 (2.00)

1.00 (1.00)

—

—

0.37

IQCODE(scores, mean ± SD)

3.07 ± 0.11

3.09 ± 0.06

3.12 ± 0.14

0.58

0.17

0.5

HAMD (scores, mean ± SD)

2.15 ± 2.38

2.14 ± 2.32

2.63 ± 2.41

0.19

0.08

0.86

Right-handedness (cases/total, %)

18/19 (94.74)

12/13 (92.31)

18/20 (90.00)

1.00

0.52

1.00

Instrumental ADL (scores, mean ± SD)

8.00 ± 0.00

8.29 ± 0.73

8.37 ± 0.90

0.17

0.001**

0.014*

Basic ADL (scores, mean ± SD)

6.00 ± 0.00

6.00 ± 0.00

6.07 ± 0.27

0.34

0.99

0.34

TOAST

LAA (cases/total,%)

—

0/13 (0.00)

2/20 (10.00)

—

—

0.51

concurrent centrum semiovale infarcts (cases/total, %)

—

0/13 (0.00)

1/20 (5.00)

—

—

1.00

Diameter of lesion (mm, mean ± SD)

—

14.55 ± 4.74

19.02 ± 9.64

—

—

0.09

Left basal ganglia (cases/total, %)

—

10/13 (76.92)

12/20 (60.00)

—

—

0.27

Hypertension (cases/total, %)

13/19 (68.42)

9/13 (69.23)

14/20 (70.00)

1.00

1.00

1.00

Impaired glucose regulation (cases/total, %)

3/19 (15.79)

2/13 (15.38)

6/20 (30.00)

1.00

0.45

0.43

Hyperlipidemia (cases/total, %)

10/19 (52.63)

8/13 (61.54)

16/20 (80.00)

0.73

0.10

0.43

Hyperhomocysteinemia (cases/total, %)

9/19 (47.37)

6/13 (46.15)

6/20 (30.00)

1.00

0.33

0.47

Peripheral arterial disease (cases/total, %)

2/19 (10.53)

3/13 (23.08)

2/20 (10.00)

0.37

1.00

0.36

Current or ever drinking (cases/total, %)

8/19 (42.11)

10/13 (76.92)

14/20 (70.00)

0.08

0.11

1.00

Current or ever smoking (cases/total, %)

8/19 (42.11)

8/13 (61.54)

12/20 (60.00)

0.47

0.34

1.00

Family history of stroke (cases/total, %)

1/19 (5.26)

1/13 (7.69)

2/20 (10.00)

1.00

1.00

1.00

Posterior circulation (case/total, %)

—

4/13 (30.77)

2/20 (10.00)

—

—

0.18

  1. NCI, no cognitive impairment; CI, cognitive impairment; NIHSS, National Institute of Health Stroke Scale; HAMD, Hamilton Depression Rating Score; ADL, Activities of Daily Living Scale; LAA, large atherothrombotic infarction; *p < 0.017, **p < 0.01. p1: NCI group vs. control group; p2: CI group vs. control group; p3: NCI group vs. CI group.
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