Figure 5 | Scientific Reports

Figure 5

From: Synthetic Lethality-based Identification of Targets for Anticancer Drugs in the Human Signaling Network

Figure 5

Illustration of our validations. (a) Anticancer drug targets validated by three aspects of the data. In the SynLethDB validation, drug sensitivity validation and text-mining validation, we validated 18, 13 and 12 anticancer drug targets, respectively. In addition, 4 targets could be validated using all three aspects. (b) The Venn diagram was drawn based on the overlap of the predicted SL gene pairs in four previous reports and our results. The methods with extremely low concordance of the results are not shown in the figure, which was drawn with the online tool http://bioinformatics.psb.ugent.be/webtools/Venn/.

Back to article page