Figure 3

Time-dependent uptake of glimepiride (A,B,C) and gliclazide (D,E,F) in OATP1B1*1a, *5, and *15-HEK293T cells. Forty micromolar glimepiride and gliclazide were incubated with OATP1B1*1a, *5, and *15-HEK293T cells for 2, 5, 10, 15, 20, 30 min. Data points represents the mean ± SD of three separate experiments.