Figure 5 | Scientific Reports

Figure 5

From: Peroxisome Proliferator-Activated Receptor gamma negatively regulates liver regeneration after partial hepatectomy via the HGF/c-Met/ERK1/2 pathways

Figure 5

Inhibition of c-Met abrogates GW9662-induced liver regeneration and hepatocyte proliferation (A) Protein expression of PPARγ, HGF/c-met signaling pathway in untreated mice, GW9662-treated mice, GW9662 plus SGX523-treated mice, and SGX523-treated mice at 0, 2, and 3 days after PH. (B) Liver to body weight ratio in control mice, GW9662-treated mice, GW9665 plus SGX523-treated mice, and SGX523-treated mice at 0, 2, and 3 days after PH. (C) Quantification of hepatic Ki67 expression and (D) PH3 expression after PH. *p < 0.05, **p < 0.01, ***p < 0.001.

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