Table 5 Association of breast cancer and reproductive factors by hormone receptor status.

From: Reproductive factors and molecular subtypes of breast cancer among premenopausal women in Latin America: the PRECAMA study

Reproductive variables

ER+ vs Control (n = 122)

ER- vs Control (n = 48)

TN vs Control (n = 36

ORa (95% CI)

p-valueb

ORa (95%CI)

p-valueb

ORa (95% CI)

p-valueb

Age at menarche (years)

1.02

(0.87–1.19)

0.84

0.63

(0.45–0.89)

0.01

0.67

(0.46–0.98)

0.04

Pregnancy ever

0.35

(0.13–0.96)

0.04

1.12

(0.22–5.72)

0.89

0.53

(0.07–3.91)

0.53

Age at FFTP (years)c

1.11

(1.04–1.19)

0.003

1.03

(0.91–1.17)

0.61

0.97

(0.84–1.13)

0.71

Time between menarche and FFTP (years)c

1.12

(1.04–1.20)

0.002

1.10

(0.97–1.26)

0.15

1.06

(0.91–1.23)

0.49

Age at last pregnancy (years)c

1.10

(1.02–1.19)

0.01

1.08

(0.94–1.25)

0.29

1.05

(0.89–1.24)

0.55

Time since last birth (years)c

0.92

(0.85–0.99)

0.02

0.95

(0.83–1.09)

0.44

0.99

(0.84–1.16)

0.88

Parityd

0.64

(0.47–0.87)

0.005

0.93

(0.54–1.58)

0.78

0.99

(0.51–1.92)

0.98

Breastfeeding everc

0.23

(0.09–0.58)

0.002

1.57

(0.46–5.43)

0.47

0.84

(0.21–3.36)

0.80

Duration of breastfeeding (months)c

0.99

(0.98–1.01)

0.48

0.97

(0.93–1.01)

0.13

0.97

(0.92–1.02)

0.20

  1. aORs are given for continuous variables (unit of change).
  2. bConditional logistic regression matched on age, country, city district, and health insurance institution and adjusted for education level, benign breast diseases, physical activity, and waist circumference.
  3. cParous women only. FFTP: first full-term pregnancy.
  4. dParity: number of childbirths.