Figure 7
From: A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye
A model to show the mechanism by Lunasin (Lun) blocks Aβ42 mediated neurodegeneration. Accumulation of Aβ42 plaques trigger a cascade of events, which activates JNK signaling. Activation of JNK signaling in the neuron triggers cell death. Misexpression of Lunasin blocks JNK signaling to promote neuroprotection of retinal neurons in the Drosophila eye.
