Figure 1
SHP deficiency in liver parenchymal cells increases mortality with lethal dose of ConA. (a) Schematic representation of the experimental set-up for preparing bone marrow chimeric mice; WT mice reconstituted with WT (WT → WT) or Shp KO (KO → WT) bone marrow-derived cells, and Shp KO mice reconstituted with Shp KO (KO → KO) or WT (WT → KO) bone marrow-derived cells. (b) Survival rate of mice injected with 27.5 mg/kg of ConA (n = 6–10 per group). Data are means ± SEMs. *P < 0.05 (log-rank test).
