Figure 3

Functional deficits precede detectable decrease in BRP at synapses of flies overexpressing Par-1. (A,B) Representative traces of EJPs (A) and mEJPs (B) from larvae overexpressing Par-1 using GeneSwitch-Elav-Gal4. Time (T) represents time after exposing larvae to the RU-486 (T₀, T₂₄, T₄₈, and T₇₂). (C–F) Quantification of EJPs (C) and mEJP amplitudes (D), frequency (E), and quantal content (F) N = 8. Error bars represent S.E.M. N.S. = p > 0.05, ^**p ≤ 0.01, ^***p ≤ 0.001, ^****p ≤ 0.0001.