Figure 2 | Scientific Reports

Figure 2

From: Antrodia cinnamomea induces autophagic cell death via the CHOP/TRB3/Akt/mTOR pathway in colorectal cancer cells

Figure 2

Effect of A. cinnamomea extract treatment on the cell viability of colorectal cancer cell lines and HPLC chemical fingerprinting. (A) HCT116, (B) HT29, (C) SW480, (D) Caco-2 and (E) Colo205 cells were treated with AC, ACF1, ACF2, and ACF3 for 48 h. The cell viability was analysed by the MTS assay and expressed as cell viability (% control). All results are expressed as the mean ± standard deviation of three independent experiments. P values of statistical significance are represented as *p < 0.05, **p < 0.005 and ***p < 0.0005. (F) HPLC chemical fingerprint of ACF2. The compounds are antcin K, antcin C, antcin H (Zhankuic acid C), dehydrosulphurenic acid, antcin B (Zhankuic acid A), antcin A, and dehydroeburicoic acid.

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