Figure 5
Effect of ACF2 treatment on tumour volume, tumour weight, and body weight in human HCT116 xenograft tumour-bearing mice. On the seventh day after tumour inoculation, the effects of ACF2 were evaluated. Animals were divided into four groups, including the control group (treated with 0.2 mL of normal saline) and the 100, 200, and 400 mg/kg ACF2 treatment groups. (A) Average tumour volume. (B) Average tumour weight. (C) Representative subcutaneous tumours in the control and 400 mg/kg ACF2 treatment groups. (D) Average body weight. All results are expressed as the mean ± standard deviation; N = 6 for all groups. P values of statistical significance are represented as *p < 0.05 and ***p < 0.0005.
